Tris(pyrazolyl)methane 99mtc tricarbonyl complexes for myocardial imaging.
نویسندگان
چکیده
Novel ether-containing tris(pyrazolyl)methane chelators stabilize thefac-[99mTc(CO)3]+ moiety providing complexes with significant, fast and stable heart uptake, together with a extremely fast liver clearance.
منابع مشابه
Photoinduced CO release, cellular uptake and cytotoxicity of a tris(pyrazolyl)methane (tpm) manganese tricarbonyl complex.
Cell viability studies of HT29 colon cancer cells treated with the CO-releasing compound [Mn(CO)(3)(tpm)]PF(6) revealed a significant photoinduced cytotoxicity comparable to that of established agent 5-fluorouracil (5-FU), while controls kept in the dark were unaffected at up to 100 microM.
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ورودعنوان ژورنال:
- Dalton transactions
دوره 4 شماره
صفحات -
تاریخ انتشار 2009